As of mid-June 2026, Madagascar has reported 689 confirmed clade I mpox cases, the highest national total globally, following the December 2025 detection of clade Ib

As of June 14, 2026, Madagascar reported 689 confirmed clade I mpox cases in the preceding six weeks, more than any other country, while the Democratic Republic of Congo and all other African nations each fell below 100 cases in the same window, continuing a downward trend in Africa-wide clade I transmission that began in May 2025